Immune correlates of tuberculosis disease and risk translate across species-Reference-Cited by-同舟云学术

Immune correlates of tuberculosis disease and risk translate across species

Published:2020-01-29 Issue:528 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ahmed Mushtaq¹^ORCID,Thirunavukkarasu Shyamala¹^ORCID,Rosa Bruce A.²^ORCID,Thomas Kimberly A.¹^ORCID,Das Shibali¹^ORCID,Rangel-Moreno Javier³,Lu Lan¹,Mehra Smriti⁴,Mbandi Stanley Kimbung⁵^ORCID,Thackray Larissa B.⁶,Diamond Michael S.¹⁶⁷,Murphy Kenneth M.⁷^ORCID,Means Terry⁸^ORCID,Martin John²,Kaushal Deepak⁹^ORCID,Scriba Thomas J.⁵^ORCID,Mitreva Makedonka²⁶^ORCID,Khader Shabaana A.¹^ORCID

Affiliation:

1. Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO 63110, USA.

2. McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63110, USA.

3. Department of Medicine, Division of Allergy, Immunology and Rheumatology, University of Rochester Medical Center, Rochester, NY 14624, USA.

4. Department of Microbiology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.

5. South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease and Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.

6. Department of Medicine, Division of Infectious Diseases, Washington University in St. Louis, St. Louis, MO 63110, USA.

7. Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO 63110, USA.

8. Autoimmunity Cluster, Immunology & Inflammation Therapeutic Area, Sanofi, Cambridge, MA 02139, USA.

9. Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX 78245, USA.

Abstract

Comparison of human TB gene signature to mouse and macaque models reveals common immune correlates of TB disease and risk.

Funder

National Institutes of Health

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference101 articles.

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4. Detection of Tuberculosis in HIV-Infected and -Uninfected African Adults Using Whole Blood RNA Expression Signatures: A Case-Control Study

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