Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease-Reference-Cited by-同舟云学术

Detection of prions in the plasma of presymptomatic and symptomatic patients with variant Creutzfeldt-Jakob disease

Published:2016-12-21 Issue:370 Volume:8 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Bougard Daisy¹,Brandel Jean-Philippe²³⁴,Bélondrade Maxime¹,Béringue Vincent⁵,Segarra Christiane¹,Fleury Hervé⁶,Laplanche Jean-Louis⁴⁷,Mayran Charly¹,Nicot Simon¹,Green Alison⁸,Welaratne Arlette³,Narbey David⁹,Fournier-Wirth Chantal¹,Knight Richard⁸,Will Robert⁸,Tiberghien Pierre⁹¹⁰,Haïk Stéphane²³⁴,Coste Joliette¹⁹

Affiliation:

1. Etablissement Français du Sang, INSERM, Université de Montpellier, UMR 1058, TransDiag, F-34184 Montpellier, France.

2. Sorbonne Universités, UPMC Univ Paris 06, INSERM, CNRS, Institut du Cerveau et de la Moelle épinière (ICM)–Hôpital Pitié-Salpêtrière, F-75013 Paris, France.

3. Assistance publique–Hôpitaux de Paris, Cellule Nationale de Référence des Maladies de Creutzfeldt-Jakob, Groupe Hospitalier Pitié-Salpêtrière, F-75013 Paris, France.

4. Centre National de Référence des Agents Transmissibles Non Conventionnels, F-75013 Paris, France.

5. Institut National de la Recherche Agronomique, Université Paris-Saclay, Virologie Immunologie Moléculaire, F-78350 Jouy-en-Josas, France.

6. Laboratoire de Virologie, Hôpital Pellegrin, F-33076 Bordeaux, France.

7. Service de Biochimie et Biologie Moléculaire, Hôpital Lariboisière, F-75010 Paris, France.

8. National Creutzfeldt-Jakob Disease Research and Surveillance Unit, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh EH4 2XU, U.K.

9. Etablissement Français du Sang, F-93218 La Plaine Saint Denis, France.

10. INSERM, Etablissement Français du Sang, Université de Franche-Comté, UMR 1098, F-25020 Besançon, France.

Abstract

A sensitive blood diagnostic assay can identify patients with variant Creutzfeldt-Jakob disease before symptoms appear and during the clinical phase.

Funder

Alliance Biosecure Foundation

INSERM

Institut de Veille Sanitaire

U.K. Department of Health Policy Research Programme

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference50 articles.

1. Transmissions to mice indicate that ‘new variant’ CJD is caused by the BSE agent

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3. Variant Creutzfeldt-Jakob disease in France and the United Kingdom: Evidence for the same agent strain

4. National Creutzfeldt-Jakob Disease Research and Surveillance Unit Variant Creutzfeldt-Jakob Disease Cases Worldwide (2016); www.cjd.ed.ac.uk/documents/worldfigs.pdf.

5. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples

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