A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates-Reference-Cited by-同舟云学术

A virus-like particle vaccine prevents equine encephalitis virus infection in nonhuman primates

Published:2019-05-15 Issue:492 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Ko Sung-Youl¹^ORCID,Akahata Wataru¹,Yang Eun Sung¹,Kong Wing-Pui¹,Burke Crystal W.²,Honnold Shelley P.³,Nichols Donald K.³,Huang Yan-Jang S.⁴^ORCID,Schieber Gretchen L.¹^ORCID,Carlton Kevin¹^ORCID,DaSilva Luis⁵^ORCID,Traina-Dorge Vicki⁶^ORCID,Vanlandingham Dana L.⁴,Tsybovsky Yaroslav⁷,Stephens Tyler⁷,Baxa Ulrich⁷,Higgs Stephen⁴^ORCID,Roy Chad J.⁶^ORCID,Glass Pamela J.²^ORCID,Mascola John R.¹^ORCID,Nabel Gary J.¹^ORCID,Rao Srinivas S.¹

Affiliation:

1. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

2. Virology Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, MD 21702, USA.

3. Pathology Division, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, MD 21702, USA.

4. Biosecurity Research Institute and Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.

5. Center for Aerobiological Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Frederick, MD 21702, USA.

6. Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.

7. Electron Microscopy Laboratory, Cancer Research Technology Program, Frederick National Laboratory for Cancer Research sponsored by the National Cancer Institute, Frederick, MD 21702, USA.

Abstract

A multivalent VLP vaccine protects against aerosol challenge of three lethal encephalitis viruses in mice and nonhuman primates.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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5. Arboviral Infections in the United States

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