Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis-Reference-Cited by-全球学者库

Multiple omics study identifies an interspecies conserved driver for nonalcoholic steatohepatitis

Published:2021-12-15 Issue:624 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Zhang Xiao-Jing¹²³^ORCID,She Zhi-Gang¹²^ORCID,Wang Junyong¹²^ORCID,Sun Dating¹²^ORCID,Shen Li-Jun¹²^ORCID,Xiang Hui¹²^ORCID,Cheng Xu¹²^ORCID,Ji Yan-Xiao²³^ORCID,Huang Yong-Ping²⁴^ORCID,Li Peng-Long²³^ORCID,Yang Xia¹²,Cheng Yanjie²⁵^ORCID,Ma Jun-Peng²³^ORCID,Wang Hai-Ping¹²,Hu Yufeng²⁵^ORCID,Hu Fengjiao²⁵,Tian Song¹²^ORCID,Tian Han¹²,Zhang Peng²³,Zhao Guang-Nian²⁵^ORCID,Wang Lin⁶^ORCID,Hu Man-Li²⁵^ORCID,Yang Qin²⁵^ORCID,Zhu Li-Hua¹²^ORCID,Cai Jingjing⁷^ORCID,Yang Juan¹²,Zhang Xin²,Ma Xinliang⁸^ORCID,Xu Qingbo⁹^ORCID,Touyz Rhian M.¹⁰^ORCID,Liu Peter P.¹¹^ORCID,Loomba Rohit¹²^ORCID,Wang Yibin¹³^ORCID,Li Hongliang¹²³⁵^ORCID

Affiliation:

1. Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan 430060, China.

2. Institute of Model Animal of Wuhan University, Wuhan 430071, China.

3. School of Basic Medical Sciences, Wuhan University, Wuhan 430071, China.

4. College of Life Sciences, Wuhan University, Wuhan 430072, China.

5. Medical Science Research Center, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.

6. Department of Hepatic Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China.

7. Department of Cardiology, The Third Xiangya Hospital, Central South University, Changsha 410013, China.

8. Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA 19004, USA.

9. Centre for Clinic Pharmacology, The William Harvey Research Institute, Queen Mary University of London, London SE5 9NU, UK.

10. British Heart Foundation Chair in Cardiovascular Medicine, and Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK.

11. Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario K1Y 4W7, Canada.

12. NAFLD Research Center, Division of Gastroenterology and Epidemiology, University of California, San Diego, San Diego, CA 92093, USA.

13. Department of Anesthesiology, Cardiovascular Research Laboratories, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

Abstract

ALOX12 drives NASH by inhibiting ACC1 lysosomal degradation across multiple species.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference73 articles.

1. Epithelial Plasticity during Liver Injury and Regeneration

2. Liver Progenitors and Adult Cell Plasticity in Hepatic Injury and Repair: Knowns and Unknowns

3. Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

4. The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

5. Innate Immune Signaling in Nonalcoholic Fatty Liver Disease and Cardiovascular Diseases

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/3;Molecular Metabolism;2024-02

2. Chronic exposure to parabens promotes non-alcoholic fatty liver disease in association with the changes of the gut microbiota and lipid metabolism;Food & Function;2024

3. ACACA reduces lipid accumulation through dual regulation of lipid metabolism and mitochondrial function via AMPK- PPARα- CPT1A axis;2023-12-15

4. Unmasking the enigma of lipid metabolism in metabolic dysfunction-associated steatotic liver disease: from mechanism to the clinic;Frontiers in Medicine;2023-11-27

5. RING finger protein 13 protects against nonalcoholic steatohepatitis by targeting STING-relayed signaling pathways;Nature Communications;2023-10-20