Intraoperative brain cancer detection with Raman spectroscopy in humans

Author:

Jermyn Michael12,Mok Kelvin3,Mercier Jeanne2,Desroches Joannie4,Pichette Julien2,Saint-Arnaud Karl2,Bernstein Liane2,Guiot Marie-Christine15,Petrecca Kevin1,Leblond Frederic2

Affiliation:

1. Brain Tumour Research Centre, Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, 3801 University Street, Montreal, Quebec H3A 2B4, Canada.

2. Department of Engineering Physics, Polytechnique Montréal, CP 6079, Succursale Centre-Ville, Montreal, Quebec H3C 3A7, Canada.

3. Neuronavigation Unit, Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec H3A 2B4, Canada.

4. Medical Physics Unit, McGill University, 1650 Cedar Avenue, Montreal, Quebec H3G 1A4, Canada.

5. Division of Neuropathology, Department of Pathology, McGill University, Montreal, Quebec H3A 2B4, Canada.

Abstract

A handheld Raman spectroscopy probe enabled detection of invasive brain cancer intraoperatively in patients with grade 2 to 4 gliomas.

Funder

Natural Sciences and Engineering Research Council of Canada

Fonds de recherche du Quebec_Nature et technologies

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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