Regulation of dendrimer/dextran material performance by altered tissue microenvironment in inflammation and neoplasia

Author:

Oliva Nuria1,Carcole Maria12,Beckerman Margarita13,Seliktar Sivan13,Hayward Alison4,Stanley James4,Parry Nicola Maria Anne5,Edelman Elazer R.16,Artzi Natalie17

Affiliation:

1. Institute for Medical Engineering and Science, Massachusetts Institute of Technology (MIT), Cambridge, MA 02139, USA.

2. Department of Industrial Engineering, Institut Quimic de Sarrià, Universitat Ramon Llull, Barcelona 08017, Spain.

3. Ort Braude College, Karmiel 21982, Israel.

4. Concord Biomedical Sciences and Emerging Technologies, Lexington, MA 02421, USA.

5. Division of Comparative Medicine, MIT, Cambridge, MA 02139, USA.

6. Cardiovascular Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

7. Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA.

Abstract

Disease type and severity spur specific tissue alterations that can guide formulation of an optimal material for a selected clinical condition.

Funder

MIT Deshpande Center for Technological Innovation

Fundacio d'Investigacio de l'Hospital Sant Pau (FISP)

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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