Disseminated Ureaplasma infection as a cause of fatal hyperammonemia in humans

Author:

Bharat Ankit1,Cunningham Scott A.2,Scott Budinger G. R.2,Kreisel Daniel3,DeWet Charl J.3,Gelman Andrew E.3,Waites Ken4,Crabb Donna4,Xiao Li4,Bhorade Sangeeta1,Ambalavanan Namasivayam4,Dilling Daniel F.567,Lowery Erin M.5,Astor Todd8,Hachem Ramsey3,Krupnick Alexander S.3,DeCamp Malcolm M.1,Ison Michael G.1,Patel Robin2

Affiliation:

1. Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

2. Mayo Clinic, Rochester, MN 55905, USA.

3. Washington University, St. Louis, MO 63110, USA.

4. University of Alabama at Birmingham, Birmingham, AL 35233, USA.

5. Loyola University Chicago Stritch School of Medicine, Chicago, IL 60153, USA.

6. Hines VA Hospital, Hines, IL, USA.

7. RML Specialty Hospital, Hinsdale, IL 60521, USA.

8. Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Abstract

Disseminated infection with Ureaplasma species causes fatal hyperammonemia syndrome in lung transplant recipients, likely by disrupting ammonia metabolism.

Funder

American Association of Thoracic Surgeons

The Barnes Jewish Research Foundation

Gibbon Research

NIH/National Institute on Alcohol Abuse and Alcoholism

Mechanisms of Lung Allograft Acceptance

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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1. Infections in Heart and Lung Transplant Recipients;Infectious Disease Clinics of North America;2024-03

2. Hyperammonemia syndrome in lung transplant recipients: A survey on current clinical practice;The Journal of Heart and Lung Transplantation;2024-02

3. Mycoplasmas and ureaplasmas;Molecular Medical Microbiology;2024

4. Mollicutes-related infections in thoracic surgery including lung and heart transplantation: A systematic review;The Journal of Heart and Lung Transplantation;2024-01

5. Treatment of Hyperammonemia Syndrome in Lung Transplant Recipients;Journal of Clinical Medicine;2023-11-08

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