The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota-Reference-Cited by-同舟云学术

The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

Published:2014-05-21 Issue:237 Volume:6 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Balmer Maria L.¹,Slack Emma¹,de Gottardi Andrea¹,Lawson Melissa A. E.¹,Hapfelmeier Siegfried²,Miele Luca³,Grieco Antonio³,Van Vlierberghe Hans⁴,Fahrner René¹,Patuto Nicola¹,Bernsmeier Christine⁵,Ronchi Francesca¹,Wyss Madeleine¹,Stroka Deborah¹,Dickgreber Nina⁶,Heim Markus H.⁵,McCoy Kathy D.¹,Macpherson Andrew J.¹

Affiliation:

1. Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse 35, CH-3010 Bern, Switzerland.

2. Institute for Infectious Diseases, University of Bern, Friedbühlstrasse 51, CH-3010 Bern, Switzerland.

3. Institute of Internal Medicine, Catholic University of Rome, Largo Agostino Gemelli 8, 00168 Rome, Italy.

4. Department of Hepatology and Gastroenterology, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium.

5. Division of Gastroenterology and Hepatology, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland.

6. Institute of Pathology, University Bern, Murtenstrasse 31, Postfach 62, CH-3010 Bern, Switzerland.

Abstract

The liver forms a firewall that protects against vascular-borne gut microbes and is commonly impaired in liver disease.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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4. Infections in Patients With Cirrhosis Increase Mortality Four-Fold and Should Be Used in Determining Prognosis

5. Severe sepsis in cirrhosis

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