Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza-Reference-Cited by-同舟云学术

Targeting Robo4-Dependent Slit Signaling to Survive the Cytokine Storm in Sepsis and Influenza

Published:2010-03-17 Issue:23 Volume:2 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

London Nyall R.¹²³,Zhu Weiquan¹²³,Bozza Fernando A.⁴,Smith Matthew C. P.¹²³,Greif Daniel M.⁵⁶,Sorensen Lise K.¹²³,Chen Luming¹²³,Kaminoh Yuuki¹²³,Chan Aubrey C.¹²³,Passi Samuel F.¹²³,Day Craig W.⁷,Barnard Dale L.⁷,Zimmerman Guy A.²,Krasnow Mark A.⁵,Li Dean Y.¹²³

Affiliation:

1. Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112, USA.

2. Department of Medicine, University of Utah, Salt Lake City, UT 84112, USA.

3. Program in Molecular Medicine, University of Utah, Salt Lake City, UT 84112, USA.

4. Intensive Care Unit, Instituto de Pesquisa Clínica Evandro Chagas, and Laboratório de Imunofarmacologia, Fundação Oswaldo Cruz, Rio de Janeiro 21045-900, Brazil.

5. Department of Biochemistry and Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

6. Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

7. Institute for Antiviral Research, Utah State University, Logan, UT 84322, USA.

Abstract

Blunting increased vascular permeability caused by an infection-induced cytokine storm with a Slit ligand increased survival in rodent models of sepsis and viral infection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference62 articles.

1. Public health risk from avian influenza viruses.;Perdue M. L.;Avian Dis.,2005

2. Bioterrorism: Management of major biological agents.;Bossi P.;Cell. Mol. Life Sci.,2006

3. Influenza virus: A master of metamorphosis.;De Jong J. C.;J. Infect.,2000

4. Next Flu Pandemic: What to Do Until the Vaccine Arrives?

5. Influenza pandemics: Past, present and future.;Hsieh Y. C.;J. Formos. Med. Assoc.,2006

Cited by 268 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Signaling pathways and potential therapeutic targets in acute respiratory distress syndrome (ARDS);Respiratory Research;2024-01-13

2. Characterizing the extracellular vesicle proteomic landscape of the human airway using in vitro organotypic multi-cellular models;iScience;2023-11

3. Recombinant Slit2 suppresses neuroinflammation and Cdc42-mediated brain infiltration of peripheral immune cells via Robo1–srGAP1 pathway in a rat model of germinal matrix hemorrhage;Journal of Neuroinflammation;2023-10-29

4. A Systematic Review of Gene Expression Studies in Critically Ill Patients with Sepsis and Community-Acquired Pneumonia;Biomedicines;2023-10-11

5. Role of the interstitium during septic shock: a key to the understanding of fluid dynamics?;Journal of Intensive Care;2023-10-10