The gut microbiota influences blood-brain barrier permeability in mice

Author:

Braniste Viorica1,Al-Asmakh Maha1,Kowal Czeslawa2,Anuar Farhana1,Abbaspour Afrouz1,Tóth Miklós3,Korecka Agata1,Bakocevic Nadja4,Ng Lai Guan4,Kundu Parag5,Gulyás Balázs35,Halldin Christer35,Hultenby Kjell6,Nilsson Harriet7,Hebert Hans7,Volpe Bruce T.8,Diamond Betty2,Pettersson Sven159

Affiliation:

1. Department of Microbiology, Tumor and Cell Biology, Karolinska Institute, 17177 Stockholm, Sweden.

2. Center for Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, NY 11030, USA.

3. Psychiatry Section, Department of Clinical Neuroscience, Karolinska Institutet, 17176 Stockholm, Sweden.

4. Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore.

5. Lee Kong Chian School of Medicine, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.

6. Department of Laboratory Medicine, Karolinska Institutet, 14186 Stockholm, Sweden.

7. Department of Biosciences and Nutrition, Karolinska Institutet, and School of Technology and Health, KTH Royal Institute of Technology, Novum, SE-141 57 Huddinge, Sweden.

8. Laboratory of Functional Neuroanatomy, The Feinstein Institute for Medical Research, North Shore-LIJ Health System, Manhasset, NY 11030, USA.

9. Singapore Centre on Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore 637551, Singapore.

Abstract

The intestinal microbiota helps to maintain the integrity of the blood-brain barrier in fetal and adult mice.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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