Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics-Reference-Cited by-同舟云学术

Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

Published:2013-05-15 Issue:185 Volume:5 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Dormitzer Philip R.¹,Suphaphiphat Pirada¹,Gibson Daniel G.²³⁴,Wentworth David E.²,Stockwell Timothy B.²,Algire Mikkel A.²,Alperovich Nina²,Barro Mario⁵,Brown David M.²,Craig Stewart¹,Dattilo Brian M.⁵,Denisova Evgeniya A.²,De Souza Ivna¹,Eickmann Markus⁶,Dugan Vivien G.²,Ferrari Annette¹,Gomila Raul C.¹⁷,Han Liqun¹,Judge Casey¹,Mane Sarthak¹,Matrosovich Mikhail⁶,Merryman Chuck³,Palladino Giuseppe¹,Palmer Gene A.¹,Spencer Terika¹⁸,Strecker Thomas⁶,Trusheim Heidi⁸,Uhlendorff Jennifer⁶,Wen Yingxia¹,Yee Anthony C.²,Zaveri Jayshree²,Zhou Bin²,Becker Stephan⁶,Donabedian Armen⁵,Mason Peter W.¹,Glass John I.²,Rappuoli Rino¹⁷,Venter J. Craig²³⁴

Affiliation:

1. Novartis Vaccines and Diagnostics, Cambridge, MA 02139, USA.

2. The J. Craig Venter Institute, Rockville, MD 20850, USA.

3. The J. Craig Venter Institute, San Diego, CA 92121, USA.

4. Synthetic Genomics Inc., La Jolla, CA 92037, USA.

5. Biomedical Advanced Research and Development Authority, U.S. Department of Health and Human Services, Washington, DC 20201, USA.

6. Institut für Virologie, Philipps-Universität Marburg, D-35032 Marburg, Germany.

7. Novartis Vaccines and Diagnostics, 53100 Siena, Italy.

8. Novartis Vaccines and Diagnostics, Holly Springs, NC 25740, USA.

Abstract

Synthesis of viral genes from sequence information allows rapid generation of influenza vaccine viruses, facilitating rapid responses to influenza pandemics.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference26 articles.

1. Real-time numerical forecast of global epidemic spreading: case study of 2009 A/H1N1pdm

2. The development of vaccine viruses against pandemic A(H1N1) influenza

3. Rapid generation of pandemic influenza virus vaccine candidate strains using synthetic DNA

4. Exploring synergies between academia and vaccine manufacturers: a pilot study on how to rapidly produce vaccines to combat emerging pathogens

5. Trivalent MDCK cell culture-derived influenza vaccine Optaflu®(Novartis Vaccines)

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