The Impact of a Consortium of Fermented Milk Strains on the Gut Microbiome of Gnotobiotic Mice and Monozygotic Twins

Author:

McNulty Nathan P.1,Yatsunenko Tanya1,Hsiao Ansel1,Faith Jeremiah J.1,Muegge Brian D.1,Goodman Andrew L.1,Henrissat Bernard2,Oozeer Raish3,Cools-Portier Stéphanie3,Gobert Guillaume3,Chervaux Christian3,Knights Dan4,Lozupone Catherine A.5,Knight Rob56,Duncan Alexis E.78,Bain James R.910,Muehlbauer Michael J.9,Newgard Christopher B.91011,Heath Andrew C.7,Gordon Jeffrey I.1

Affiliation:

1. Center for Genome Sciences and Systems Biology, Washington University School of Medicine, St. Louis, MO 63108, USA.

2. Architecture et Fonction des Macromolécules Biologiques, CNRS, 13288 Marseille Cedex 9, France.

3. Danone Research, 91 767 Palaiseau Cedex, France.

4. Department of Computer Science, University of Colorado, Boulder, CO 80309, USA.

5. Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA.

6. Howard Hughes Medical Institute, University of Colorado, Boulder, CO 80309, USA.

7. Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63108, USA.

8. George Warren Brown School of Social Work, Washington University, St. Louis, MO 63130, USA.

9. Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA.

10. Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

11. Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC 27710, USA.

Abstract

Metagenomic analyses of gnotobiotic mice and monozygotic twins reveal the effects of eating a popular fermented milk product on their microbiomes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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