Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer

Author:

Stott Shannon L.123,Lee Richard J.45,Nagrath Sunitha123,Yu Min4,Miyamoto David T.46,Ulkus Lindsey4,Inserra Elizabeth J.4,Ulman Matthew4,Springer Simeon4,Nakamura Zev4,Moore Alessandra L.1,Tsukrov Dina I.1,Kempner Maria E.4,Dahl Douglas M.27,Wu Chin-Lee48,Iafrate A. John48,Smith Matthew R.45,Tompkins Ronald G.23,Sequist Lecia V.45,Toner Mehmet123,Haber Daniel A.45,Maheswaran Shyamala34

Affiliation:

1. Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

2. Shriners Hospital for Children, Harvard Medical School, Boston, MA 02114, USA.

3. Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

4. Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.

5. Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

6. Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

7. Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

8. Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Abstract

Automated imaging of prostate-specific cancer cells from the blood provides a measure of circulating tumor cell half-life after tumor resection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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