Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

Author:

Getts Daniel R.123,Terry Rachael L.12,Getts Meghann Teague2,Deffrasnes Celine1,Müller Marcus4,van Vreden Caryn1,Ashhurst Thomas M.1,Chami Belal1,McCarthy Derrick2,Wu Huiling5,Ma Jin5,Martin Aaron2,Shae Lonnie D.6,Witting Paul1,Kansas Geoffrey S.2,Kühn Joachim7,Hafezi Wali7,Campbell Iain L.8,Reilly David9,Say Jana10,Brown Louise10,White Melanie Y.8,Cordwell Stuart J.8,Chadban Steven J.5,Thorp Edward B.11,Bao Shisan1,Miller Stephen D.2,King Nicholas J. C.1

Affiliation:

1. The Discipline of Pathology, School of Medical Sciences, Bosch Institute, Sydney Medical School, University of Sydney, Sydney, New South Wales 2006, Australia.

2. Departments of Microbiology-Immunology and Interdepartmental Immunobiology Center, Feinberg School of Medicine, Northwestern University, Elmhurst, IL 60611, USA.

3. Cour Pharmaceutical Development Company, Elmhurst, IL 60126, USA.

4. Department of Neurology, Universitätsklinikum Bonn, Bonn 53113, Germany.

5. Collaborative Transplant Research Group, Renal Medicine, Royal Prince Alfred Hospital, University of Sydney, Sydney, New South Wales 2006, Australia.

6. Department of Chemical and Biological Engineering, McCormick School of Engineering, Northwestern University, Evanston, IL 60208, USA.

7. University Hospital Münster, Institute of Medical Microbiology—Clinical Virology, Interdisciplinary Center of Clinical Research, Münster 48419, Germany.

8. School of Molecular Bioscience, University of Sydney, Sydney, New South Wales 2006, Australia.

9. The School of Physics, University of Sydney, Sydney, New South Wales 2006, Australia.

10. Department of Chemistry and Biomolecular Science, Macquarie University, Sydney, New South Wales 2109, Australia.

11. Department of Pathology and Feinberg Cardiovascular Research Institute, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

Abstract

Negatively charged immune-modifying microparticles bind to the scavenger receptor MARCO on inflammatory monocytes, resulting in their apoptosis and reduced inflammatory damage in a range of diseases.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Cited by 274 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3