Patient-Specific Induced Pluripotent Stem Cells as a Model for Familial Dilated Cardiomyopathy

Author:

Sun Ning123,Yazawa Masayuki4,Liu Jianwei5,Han Leng12,Sanchez-Freire Veronica12,Abilez Oscar J.6,Navarrete Enrique G.2,Hu Shijun12,Wang Li123,Lee Andrew123,Pavlovic Aleksandra1,Lin Shin1,Chen Rui7,Hajjar Roger J.8,Snyder Michael P.7,Dolmetsch Ricardo E.4,Butte Manish J.5,Ashley Euan A.1,Longaker Michael T.39,Robbins Robert C.10,Wu Joseph C.12310

Affiliation:

1. Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

2. Department of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

3. Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

4. Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA.

5. Department of Pediatrics, Division of Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA.

6. Division of Vascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

7. Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.

8. Department of Gene and Cell Medicine, Mount Sinai Medical Center, Stanford University School of Medicine, Stanford, CA 94305, USA.

9. Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

10. Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Abstract

Human induced pluripotent stem cells generated from patients with familial dilated cardiomyopathy model cardiovascular disease in these patients.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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