An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs

Author:

Huang Ke12ORCID,Ozpinar Emily W.23ORCID,Su Teng123ORCID,Tang Junnan1,Shen Deliang1,Qiao Li1,Hu Shiqi13ORCID,Li Zhenhua13ORCID,Liang Hongxia1,Mathews Kyle24,Scharf Valery4,Freytes Donald O.23,Cheng Ke1234ORCID

Affiliation:

1. Department of Molecular Biomedical Sciences, North Carolina State University, Raleigh, NC 27607, USA.

2. Comparative Medicine Institute, North Carolina State University, Raleigh, NC 27607, USA.

3. Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC 27607, USA.

4. Department of Clinical Sciences, North Carolina State University, Raleigh, NC 27607, USA.

Abstract

Acellular patches embedded with encapsulated cell-secreted factors improve cardiac repair after acute myocardial infarction in rodents and pigs.

Funder

National Institutes of Health

American Heart Association

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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