PIEZO2 mediates injury-induced tactile pain in mice and humans-Reference-Cited by-同舟云学术

PIEZO2 mediates injury-induced tactile pain in mice and humans

Published:2018-10-10 Issue:462 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Szczot Marcin¹^ORCID,Liljencrantz Jaquette¹^ORCID,Ghitani Nima¹^ORCID,Barik Arnab¹^ORCID,Lam Ruby¹^ORCID,Thompson James H.¹^ORCID,Bharucha-Goebel Diana²³,Saade Dimah²^ORCID,Necaise Aaron¹,Donkervoort Sandra²,Foley A. Reghan²,Gordon Taylor¹,Case Laura¹^ORCID,Bushnell M. Catherine¹,Bönnemann Carsten G.²^ORCID,Chesler Alexander T.¹

Affiliation:

1. National Center for Complementary and Integrative Health, National Institutes of Health, Bethesda, MD 20892, USA.

2. National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

3. Department of Neurology, Children’s National Medical Center, Washington, DC 20010, USA.

Abstract

The stretch-gated ion channel PIEZO2 is required for inflammation-induced tactile allodynia.

Funder

National Center for Complementary and Alternative Medicine

National Institute of Neurological Disorders and Stroke

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference35 articles.

1. Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

2. The Role of PIEZO2 in Human Mechanosensation

3. Piezo2 is the major transducer of mechanical forces for touch sensation in mice

4. The role of Drosophila Piezo in mechanical nociception

5. Nociceptor sensitization in pain pathogenesis

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