Astrocyte molecular signatures in Huntington’s disease-Reference-Cited by-同舟云学术

Astrocyte molecular signatures in Huntington’s disease

Published:2019-10-16 Issue:514 Volume:11 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Diaz-Castro Blanca¹^ORCID,Gangwani Mohitkumar R.¹^ORCID,Yu Xinzhu¹^ORCID,Coppola Giovanni²³⁴^ORCID,Khakh Baljit S.¹⁵^ORCID

Affiliation:

1. Department of Physiology, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA.

2. Department of Neurology, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA.

3. Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA.

4. Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA.

5. Department of Neurobiology, University of California, Los Angeles, Los Angeles, CA 90095-1751, USA.

Abstract

Astrocyte gene expression is altered in mouse models of Huntington’s disease and in postmortem brain samples from patients with HD.

Funder

National Institute of Neurological Disorders and Stroke

National Institute of Child Health and Human Development

American Heart Association

CHDI Foundation

NIMH

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference41 articles.

1. Diversity of astrocyte functions and phenotypes in neural circuits

2. Do glia drive synaptic and cognitive impairment in disease?

3. Huntington disease

4. Clinical Features of Huntington’s Disease

5. The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

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