Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4 + T cells-Reference-Cited by-全球学者库

Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4 + T cells

Published:2015-10-21 Issue:310 Volume:7 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Mou Zhirong¹,Li Jintao¹²,Boussoffara Thouraya³,Kishi Hiroyuki⁴,Hamana Hiroshi⁴,Ezzati Peyman⁵,Hu Chuanmin⁶,Yi Weijing⁶,Liu Dong¹,Khadem Forough¹,Okwor Ifeoma⁷,Jia Ping¹,Shitaoka Kiyomi⁴,Wang Shufeng⁸,Ndao Momar⁹,Petersen Christine¹⁰,Chen Jianping¹¹,Rafati Sima¹²,Louzir Hechmi³,Muraguchi Atsushi⁴,Wilkins John A.⁵,Uzonna Jude E.¹⁷

Affiliation:

1. Department of Immunology, College of Medicine, University of Manitoba, Winnipeg, Manitoba R3T 0T5, Canada.

2. Institute of Tropical Medicine, Third Military Medical University, Chongqing 400038, China.

3. Laboratory of Transmission, Control and Immunobiology of Infections, Pasteur Institute of Tunis, Tunis 1002, Tunisia.

4. Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan.

5. Manitoba Centre for Proteomics and Systems Biology, Department of Internal Medicine, University of Manitoba, Health Sciences Centre, Winnipeg, Manitoba R3E 3P4, Canada.

6. Department of Clinical Biochemistry, Laboratory Sciences, Third Military Medical University, Chongqing 400038, China.

7. Department of Medical Microbiology, College of Medicine, University of Manitoba, Winnipeg, Manitoba R3E 0J9, Canada.

8. Department of Immunology, Third Military Medical University, Chongqing 400038, China.

9. National Reference Centre for Parasitology, Department of Medicine, Division of Infectious Diseases, McGill University, Montreal, Quebec H3G 1A4, Canada.

10. Department of Epidemiology, University of Iowa, Iowa City, IA 52242 USA.

11. Department of Parasitology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610065, China.

12. Molecular Immunology and Vaccine Research Laboratory, Pasteur Institute of Iran, Tehran 13164, Iran.

Abstract

A Leishmania protein vaccine elicited immune responses and mediated strong cross-species protection.

Funder

Research Manitoba

Canadian Institutes for Health Research

National Natural Science Foundation of China

Manitoba Institute of Child Health

Publisher

American Association for the Advancement of Science (AAAS)