Bilirubin enhances the activity of ASIC channels to exacerbate neurotoxicity in neonatal hyperbilirubinemia in mice-Reference-Cited by-同舟云学术

Bilirubin enhances the activity of ASIC channels to exacerbate neurotoxicity in neonatal hyperbilirubinemia in mice

Published:2020-02-12 Issue:530 Volume:12 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Lai Ke¹^ORCID,Song Xing-Lei²^ORCID,Shi Hao-Song¹,Qi Xin²^ORCID,Li Chun-Yan¹,Fang Jia¹,Wang Fan¹,Maximyuk Oleksandr³^ORCID,Krishtal Oleg³^ORCID,Xu Tian-Le²^ORCID,Li Xiao-Yan⁴,Ni Kun⁴,Li Wan-Peng⁴,Shi Hai-Bo¹^ORCID,Wang Lu-Yang⁵⁶^ORCID,Yin Shan-Kai¹

Affiliation:

1. Department of Otorhinolaryngology, Sixth People’s Hospital of Shanghai and Shanghai Jiao Tong University, Shanghai 200032, China.

2. Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

3. Bogomoletz Institute of Physiology of NAS Ukraine, Kyiv 01024, Ukraine.

4. Department of Otorhinolaryngology, Shanghai Children Hospital and Shanghai Jiao Tong University, Shanghai 200062, China.

5. Program in Neuroscience and Mental Health, SickKids Research Institute, Toronto M5G 1X8, Canada.

6. Department of Physiology, University of Toronto, Toronto M5S 1A1, Canada.

Abstract

Neonatal hyperbilirubinemia aggravates acidosis-dependent long-term brain injury.

Funder

Canadian Institutes of Health Research

National Natural Science Foundation of China

Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support

Shanghai Outstanding Academic Leaders Plan

The Science and Technology Commission of Shanghai Municipality and the Innovative Research Team of High-level Local Universities in Shanghai

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference73 articles.

1. Brainstem auditory evoked potentials correlate with morphological changes in Gunn rat pups

2. Changes in calcium-binding protein expression in the auditory brainstem nuclei of the jaundiced Gunn rat

3. Bilirubin induces auditory neuropathy in neonatal guinea pigs via auditory nerve fiber damage

4. Kernicterus and the Molecular Mechanisms of Bilirubin-Induced CNS Injury in Newborns

5. The impact of SLCO1B1 genetic polymorphisms on neonatal hyperbilirubinemia: a systematic review with meta-analysis

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