Nanofiber-hydrogel composite–mediated angiogenesis for soft tissue reconstruction

Author:

Li Xiaowei123ORCID,Cho Brian4ORCID,Martin Russell123ORCID,Seu Michelle4ORCID,Zhang Chi123ORCID,Zhou Zhengbing123,Choi Ji Suk123ORCID,Jiang Xuesong123ORCID,Chen Long123ORCID,Walia Gurjot4ORCID,Yan Jerry5,Callanan Megan5,Liu Huanhuan123,Colbert Kevin12ORCID,Morrissette-McAlmon Justin15,Grayson Warren125ORCID,Reddy Sashank4ORCID,Sacks Justin M.4,Mao Hai-Quan1235ORCID

Affiliation:

1. Translational Tissue Engineering Center, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

2. Institute for NanoBioTechnology, Johns Hopkins University, Baltimore, MD 21218, USA.

3. Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

4. Department of Plastic and Reconstructive Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.

5. Department of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.

Abstract

A biodegradable nanofiber-hydrogel composite material promotes angiogenesis for soft tissue reconstruction in rodent and rabbit models.

Funder

National Science Foundation

Maryland Stem Cell Research Fund

NIH

AHA

Coulter Foundation Translational Grant

Cohen Translational Engineering Fund

Louis B. Thalheimer Award for Translational Research

Abell Foundation Translational Award

Maryland Innovation Initiative

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

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