Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates-Reference-Cited by-同舟云学术

Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates

Published:2021-03-10 Issue:584 Volume:13 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Li Qingju¹²^ORCID,Xu Yinchuan¹²^ORCID,Lv Kaiqi²^ORCID,Wang Yingchao²³,Zhong Zhiwei²³,Xiao Changchen¹²,Zhu Keyang²,Ni Cheng¹,Wang Kan¹,Kong Minjian⁴,Li Xuebiao⁴,Fan Youqi¹,Zhang Fengjiang⁵,Chen Qi⁵,Li Yi⁵,Li Qian⁶,Liu Chengjia⁶,Zhu Jinyun¹,Zhong Shuhan²,Wang Jingyi²,Chen Yongjian²,Zhao Jing²³,Zhu Dan¹²,Wu Rongrong²,Chen Jinghai²⁷^ORCID,Zhu Wei²,Yu Hong²,Ardehali Reza⁸^ORCID,Zhang Jianyi(Jay)⁹^ORCID,Wang Jian’an¹²^ORCID,Hu Xinyang¹²^ORCID

Affiliation:

1. Department of Cardiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, PR China.

2. Cardiovascular Key Laboratory of Zhejiang Province, Hangzhou 310009, PR China.

3. Deptartment of Laboratory Medicine, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, PR China.

4. Department of Cardiovascular Surgery, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, PR China.

5. Deptartment of Anesthesiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, PR China.

6. Deptartment of Radiology, Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, PR China.

7. Department of Cardiology, Second Affiliated Hospital, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou 310009, China.

8. Division of Cardiology, Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90001, USA.

9. Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35233, USA.

Abstract

Extracellular vesicles containing miR-486-5p augment angiogenesis after MI in mice and nonhuman primates by targeting fibroblastic Mmp19 .

Funder

National Natural Science Foundation of China

The Key R & D projects of Zhejiang Province

the Fundamental Research Funds for the Central Universities

National Key Research and Development Program of China Stem Cell and Translational Research

Natural Science Foundation of Zhejiang Province

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference32 articles.

1. Angiogenic Endothelial Cell Signaling in Cardiac Hypertrophy and Heart Failure

2. Approaches to therapeutic angiogenesis for ischemic heart disease

3. Endothelial C-Type Natriuretic Peptide Is a Critical Regulator of Angiogenesis and Vascular Remodeling

4. Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction

5. The Secret Life of Exosomes

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