Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity-Reference-Cited by-同舟云学术

Global and local envelope protein dynamics of hepatitis C virus determine broad antibody sensitivity

Published:2020-08-28 Issue:35 Volume:6 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Augestad Elias H.¹^ORCID,Castelli Matteo²,Clementi Nicola²^ORCID,Ströh Luisa J.³^ORCID,Krey Thomas³⁴⁵⁶⁷^ORCID,Burioni Roberto²,Mancini Nicasio²^ORCID,Bukh Jens¹^ORCID,Prentoe Jannick¹^ORCID

Affiliation:

1. Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark.

2. Laboratory of Microbiology and Virology, Università “Vita-Salute” San Raffaele, Milano, 20132, Italy.

3. Institute of Virology, Hannover Medical School, Carl-Neuberg-Str. 1, Hannover 30625, Germany.

4. German Center for Infection Research (DZIF), partner sites Hannover-Braunschweig and Hamburg-Lübeck-Borstel-Riems, Germany.

5. Center of Structural and Cell Biology in Medicine, Institute of Biochemistry, University of Luebeck, Ratzeburger Allee 160, 23562 Luebeck, Germany.

6. Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.

7. Centre for Structural Systems Biology (CSSB), Notkestraße 85, 22607 Hamburg, Germany.

Abstract

New insights into hepatitis C virus evasion from neutralizing antibodies have important implications for vaccine development.

Funder

Deutsche Forschungsgemeinschaft

Lundbeckfonden

Novo Nordisk Fonden

Candys Foundation

Innovation Fund Denmark

Independent Research Fund Denmark

Danish Council for Independent Research, Medical Sciences