Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors

Author:

Peinetti Ana S.1ORCID,Lake Ryan J.1ORCID,Cong Wen2ORCID,Cooper Laura3ORCID,Wu Yuting1ORCID,Ma Yuan1ORCID,Pawel Gregory T.1ORCID,Toimil-Molares María Eugenia4ORCID,Trautmann Christina45ORCID,Rong Lijun3ORCID,Mariñas Benito2ORCID,Azzaroni Omar6ORCID,Lu Yi1ORCID

Affiliation:

1. Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

2. Department of Civil and Environmental Engineering, Safe Global Water Institute, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

3. Department of Microbiology and Immunology, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA.

4. GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt 64291, Germany.

5. Technische Universitat Darmstadt, Darmstadt 64287, Germany.

6. Instituto de Investigaciones Fisicoquímicas Teóricas y Aplicadas (INIFTA), Departamento de Química, Facultad de Ciencias Exactas, Universidad Nacional de La Plata (UNLP), CONICET, Boulevard 113 y 64, La Plata 1900, Argentina.

Abstract

Novel sensors can not only detect SARS-CoV-2 or other viruses in real-world samples but also determine if they are infectious.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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