Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell-Reference-Cited by-同舟云学术

Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

Published:2021-02-05 Issue:6 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Kildisiute Gerda¹^ORCID,Kholosy Waleed M.²^ORCID,Young Matthew D.¹^ORCID,Roberts Kenny¹^ORCID,Elmentaite Rasa¹^ORCID,van Hooff Sander R.²,Pacyna Clarissa N.¹^ORCID,Khabirova Eleonora¹,Piapi Alice³,Thevanesan Christine³^ORCID,Bugallo-Blanco Eva³^ORCID,Burke Christina³^ORCID,Mamanova Lira¹^ORCID,Keller Kaylee M.²,Langenberg-Ververgaert Karin P.S.²^ORCID,Lijnzaad Philip²^ORCID,Margaritis Thanasis²^ORCID,Holstege Frank C.P.²^ORCID,Tas Michelle L.²^ORCID,Wijnen Marc H.W.A.²,van Noesel Max M.²,del Valle Ignacio³^ORCID,Barone Giuseppe⁴^ORCID,van der Linden Reinier⁵^ORCID,Duncan Catriona⁴^ORCID,Anderson John³⁴^ORCID,Achermann John C.³^ORCID,Haniffa Muzlifah¹⁶⁷^ORCID,Teichmann Sarah A.¹^ORCID,Rampling Dyanne⁴^ORCID,Sebire Neil J.⁴^ORCID,He Xiaoling⁸⁹,de Krijger Ronald R.²¹⁰,Barker Roger A.⁸⁹^ORCID,Meyer Kerstin B.¹^ORCID,Bayraktar Omer¹,Straathof Karin³⁴^ORCID,Molenaar Jan J.²^ORCID,Behjati Sam¹¹¹¹²^ORCID

Affiliation:

1. Wellcome Sanger Institute, CB10 1SA Hinxton, UK.

2. Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS Utrecht, Netherlands.

3. UCL Great Ormond Street Institute of Child Health, WC1N 1EH London, UK.

4. Great Ormond Street Hospital for Children (GOSH), NHS Foundation Trust, NIHR Great Ormond Street Hospital Biomedical Research Centre, WC1N 3JH London, UK.

5. Hubrecht Institute, KNAW, 3584 CT Utrecht, Netherlands.

6. Institute of Cellular Medicine, Newcastle University, NE2 4HH Newcastle upon Tyne, UK.

7. Department of Dermatology and NIHR Newcastle Biomedical Research Centre, Newcastle Hospitals, NHS Foundation Trust, NE2 4LP Newcastle upon Tyne, UK.

8. MRC-WT Cambridge Stem Cell Institute, University of Cambridge, CB2 0QQ Cambridge, UK.

9. Department of Clinical Neurosciences, University of Cambridge, CB2 0QQ Cambridge, UK.

10. Department of Pathology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, Netherlands.

11. Cambridge University Hospitals NHS Foundation Trust, CB2 0QQ Cambridge, UK.

12. Department of Paediatrics, University of Cambridge, CB2 0QQ Cambridge, UK.

Abstract

Comparisons of neuroblastoma cells and relevant normal adrenal cells reveal a uniform cell state that characterizes neuroblastoma.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference58 articles.

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4. Neuroblastoma stage 4S: a multifocal stem-cell disease of the developing neural crest

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