A neuronal molecular switch through cell-cell contact that regulates quiescent neural stem cells

Author:

Dong Jian12ORCID,Pan Yuan-Bo3,Wu Xin-Rong4,He Li-Na1,Liu Xian-Dong12,Feng Dong-Fu3,Xu Tian-Le12ORCID,Sun Suya4ORCID,Xu Nan-Jie1256ORCID

Affiliation:

1. Collaborative Innovation Center for Brain Science, Department of Anatomy and Physiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

2. Department of Biochemistry and Molecular Cell Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

3. Department of Neurosurgery, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

4. Department of Neurology, Institute of Neurology, Rui-jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

5. Key Laboratory of Cell Differentiation and Apoptosis of the Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

6. Shanghai Key Laboratory of Reproductive Medicine, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Abstract

Excitatory hippocampal granule cells regulate activation and transition of quiescent neural stem cells during voluntary exercise.

Funder

National Basic Research Program of China

Shanghai Committee of Science and Technology

the Science and Technology Commission of Shanghai Municipality

National Natural and Science Foundation of China

Grants of Shanghai Brain-Intelligence Project from STCSM

The Recruitment Program of Global Experts for Young Professionals

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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