Wireless, battery-free optoelectronic systems as subdermal implants for local tissue oximetry

Author:

Zhang Hao1ORCID,Gutruf Philipp123ORCID,Meacham Kathleen4ORCID,Montana Michael C.4,Zhao Xingyue56,Chiarelli Antonio M.7,Vázquez-Guardado Abraham8,Norris Aaron4,Lu Luyao5,Guo Qinglei59ORCID,Xu Chenkai10ORCID,Wu Yixin1ORCID,Zhao Hangbo2ORCID,Ning Xin5ORCID,Bai Wubin12,Kandela Irawati1112ORCID,Haney Chad R.101213ORCID,Chanda Debashis8,Gereau Robert W.414ORCID,Rogers John A.15ORCID

Affiliation:

1. Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA.

2. Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.

3. Department of Biomedical Engineering, University of Arizona, Tucson, AZ 85721, USA.

4. Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

5. Department of Materials Science and Engineering and Frederick Seitz Materials Research Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.

6. State Key Laboratory of New Ceramics and Fine Processing and School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.

7. Institute of Advanced Biomedical Technologies and Department of Neuroscience, Imaging and Clinical Sciences, University G. D’Annunzio of Chieti–Pescara, Chieti 66100, Italy.

8. NanoScience Technology Center, Department of Physics and CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, FL 32826, USA.

9. Department of Materials Science, Fudan University, Shanghai 200433, China.

10. Department of Biomedical Engineering, Northwestern University, Evanston, IL 60208, USA.

11. Developmental Therapeutics Core, Northwestern University, Evanston, IL 60208, USA.

12. Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.

13. Center for Advanced Molecular Imaging, Northwestern University, Evanston, IL 60208, USA.

14. Washington University Pain Center, Washington University School of Medicine, St. Louis, MO 63110, USA.

15. Departments of Materials Science and Engineering, Biomedical Engineering, Neurological Surgery, Chemistry, Mechanical Engineering, Electrical Engineering and Computer Science, Simpson Querrey Institute and Feinberg Medical School, Center for Bio-Integrated Electronics, Northwestern University, Evanston, IL 60208, USA.

Abstract

Wireless, battery-free optoelectronic systems enable localized tissue oximetry in tether-free, awake animal models.

Funder

National Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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