Exercise training improves motor skill learning via selective activation of mTOR

Author:

Chen Kai1ORCID,Zheng Yuhan1,Wei Ji-an1,Ouyang Huan1,Huang Xiaodan1,Zhang Feilong2,Lai Cora Sau Wan34ORCID,Ren Chaoran156,So Kwok-Fai1456ORCID,Zhang Li16ORCID

Affiliation:

1. Joint International Research Laboratory of CNS Regeneration, Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou 510632, P. R. China.

2. Peking University, Drug Discovery Center, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, P. R. China.

3. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.

4. State Key Laboratory of Brain and Cognitive Science, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, P. R. China.

5. Co-innovation Center of Neuroregeneration, Nantong University, Jiangsu 226019, P. R. China.

6. Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510530, P. R. China.

Abstract

Our ex vivo and in vivo studies demonstrate a molecular pathway for exercise-induced learning enhancement.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Guangdong Natural Science Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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