Disparities in dermatology AI performance on a diverse, curated clinical image set

Author:

Daneshjou Roxana12ORCID,Vodrahalli Kailas3ORCID,Novoa Roberto A.14,Jenkins Melissa1,Liang Weixin5,Rotemberg Veronica6ORCID,Ko Justin1,Swetter Susan M.1ORCID,Bailey Elizabeth E.1,Gevaert Olivier2ORCID,Mukherjee Pritam2ORCID,Phung Michelle1,Yekrang Kiana1ORCID,Fong Bradley1,Sahasrabudhe Rachna1ORCID,Allerup Johan A. C.1ORCID,Okata-Karigane Utako7ORCID,Zou James2358,Chiou Albert S.1ORCID

Affiliation:

1. Department of Dermatology, Stanford School of Medicine, Redwood City, CA, USA.

2. Department of Biomedical Data Science, Stanford School of Medicine, Stanford, CA, USA.

3. Department of Electrical Engineering, Stanford University, Stanford, CA, USA.

4. Department of Pathology, Stanford School of Medicine, Stanford, CA, USA.

5. Department of Computer Science, Stanford University, Stanford, CA, USA.

6. Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

7. Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.

8. Chan-Zuckerberg Biohub, San Francisco, CA, USA.

Abstract

An estimated 3 billion people lack access to dermatological care globally. Artificial intelligence (AI) may aid in triaging skin diseases and identifying malignancies. However, most AI models have not been assessed on images of diverse skin tones or uncommon diseases. Thus, we created the Diverse Dermatology Images (DDI) dataset—the first publicly available, expertly curated, and pathologically confirmed image dataset with diverse skin tones. We show that state-of-the-art dermatology AI models exhibit substantial limitations on the DDI dataset, particularly on dark skin tones and uncommon diseases. We find that dermatologists, who often label AI datasets, also perform worse on images of dark skin tones and uncommon diseases. Fine-tuning AI models on the DDI images closes the performance gap between light and dark skin tones. These findings identify important weaknesses and biases in dermatology AI that should be addressed for reliable application to diverse patients and diseases.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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