Nanovesicles derived from iron oxide nanoparticles–incorporated mesenchymal stem cells for cardiac repair

Author:

Lee Ju-Ro1ORCID,Park Bong-Woo2ORCID,Kim Jonghoon13,Choo Yeon Woong1ORCID,Kim Han Young1ORCID,Yoon Jeong-Kee1,Kim Hyeok24ORCID,Hwang Ji-Won24ORCID,Kang Mikyung5ORCID,Kwon Sung Pil1,Song Seuk Young1ORCID,Ko In Ok6ORCID,Park Ji-Ae6ORCID,Ban Kiwon7ORCID,Hyeon Taeghwan138ORCID,Park Hun-Jun249ORCID,Kim Byung-Soo18ORCID

Affiliation:

1. School of Chemical and Biological Engineering, Seoul National University, Seoul 08826, Republic of Korea.

2. Department of Medical Life Science, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

3. Center for Nanoparticle Research, Institute of Basic Science (IBS), Seoul 08826, Republic of Korea.

4. Division of Cardiology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul 06591, Republic of Korea.

5. Interdisciplinary Program for Bioengineering, Seoul National University, Seoul 08826, Republic of Korea.

6. Division of Applied RI, Korea Institute Radiological and Medical Sciences, Seoul 01812, Republic of Korea.

7. Department of Biomedical Sciences, City University of Hong Kong, Kowloon Tong, Hong Kong.

8. Institute of Chemical Processes, Institute of Engineering Research, BIOMAX, Seoul National University, Seoul 08826, Republic of Korea.

9. Cell Death Disease Research Center, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.

Abstract

Increased therapeutic factors and retention of IONP-NVs substantially enhance therapeutic potential for cardiac repair.

Funder

Ministry of Health and Welfare

National Research Foundation of Korea

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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