A 3D atlas of the dynamic and regional variation of pancreatic innervation in diabetes

Author:

Alvarsson Alexandra1ORCID,Jimenez-Gonzalez Maria1ORCID,Li Rosemary1ORCID,Rosselot Carolina1ORCID,Tzavaras Nikolaos2ORCID,Wu Zhuhao34ORCID,Stewart Andrew F.1ORCID,Garcia-Ocaña Adolfo15ORCID,Stanley Sarah A.14ORCID

Affiliation:

1. Diabetes, Obesity, and Metabolism Institute, Division of Endocrinology, Diabetes and Bone Diseases, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

2. The Microscopy CoRE and Advanced Bioimaging Center, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

3. Department of Cell, Developmental & Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

4. Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

5. The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

Abstract

Three-dimensional mapping of pancreatic innervation shows rapid remodeling of islet innervation in mouse and human diabetes.

Funder

National Institutes of Health

National Institute of Mental Health

American Diabetes Association

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Neurological Disorders and Stroke

Einstein-Mount Sinai Diabetes Research Center, Albert Einstein College of Medicine

JDRF

Charles H. Revson Foundation

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference78 articles.

1. Signals in the pancreatic islet microenvironment influence β-cell proliferation;Aamodt K. I.;Diabetes Obes. Metab.,2017

2. Autonomic regulation of islet hormone secretion—Implications for health and disease;Ahrén B.;Diabetologia,2000

3. Innervation patterns of autonomic axons in the human endocrine pancreas;Rodriguez-Diaz R.;Cell Metab.,2011

4. J. Gerald J. Taborsky Handbook of Physiology (Oxford Univ. Press American Physiological Society 2001).

5. Bidirectional electromagnetic control of the hypothalamus regulates feeding and metabolism

Cited by 34 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3