Discovery of an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes-Reference-Cited by-同舟云学术

Discovery of an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes

Published:2021-11-19 Issue:47 Volume:7 Page:
ISSN:2375-2548
Container-title:Science Advances
language:en
Short-container-title:Sci. Adv.

Author:

Takagi Takeru¹^ORCID,Ueno Tasuku¹^ORCID,Ikawa Keisuke²³^ORCID,Asanuma Daisuke⁴⁵^ORCID,Nomura Yusuke¹,Uno Shin-nosuke⁴^ORCID,Komatsu Toru¹^ORCID,Kamiya Mako⁴^ORCID,Hanaoka Kenjiro¹⁶,Okimura Chika⁷,Iwadate Yoshiaki⁷^ORCID,Hirose Kenzo⁴⁸^ORCID,Nagano Tetsuo⁹,Sugimura Kaoru²³^ORCID,Urano Yasuteru¹⁴¹⁰^ORCID

Affiliation:

1. Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

2. Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Yayoi 2-11-16, Bunkyo-ku, Tokyo 113-0032, Japan.

3. Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Yoshida-Ushinomiya-cho, Sakyo-ku, Kyoto 606-8501, Japan.

4. Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

5. PRESTO, Japan Science and Technology Agency (JST), 4-1-8 Honcho, Kawaguchi-shi, Saitama 332-0012, Japan.

6. Faculty of Pharmacy, Keio University, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan.

7. Faculty of Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi 753-8512, Japan.

8. International Research Center for Neurointelligence, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

9. Drug Discovery Initiative, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

10. Core Research for Evolutional Science and Technology (CREST) Investigator, Japan Agency for Medical Research and Development (AMED), 1-7-1 Otemachi, Chiyoda-ku, Tokyo 100-0004, Japan.

Abstract

We found an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

Reference37 articles.

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