A wireless and battery-free wound infection sensor based on DNA hydrogel

Author:

Xiong Ze123ORCID,Achavananthadith Sippanat1ORCID,Lian Sophie4ORCID,Madden Leigh Edward56ORCID,Ong Zi Xin567ORCID,Chua Wisely8,Kalidasan Viveka1ORCID,Li Zhipeng1ORCID,Liu Zhu1ORCID,Singh Priti9ORCID,Yang Haitao10ORCID,Heussler Sascha P.11ORCID,Kalaiselvi S. M. P.12ORCID,Breese Mark B. H.12ORCID,Yao Haicheng13ORCID,Gao Yuji2ORCID,Sanmugam Kavitha14,Tee Benjamin C. K.1231315ORCID,Chen Po-Yen10ORCID,Loke Weiqiang9ORCID,Lim Chwee Teck241516ORCID,Chiang Grace Shu Hui14,Tan Boon Yeow14,Li Hao717ORCID,Becker David Laurence56ORCID,Ho John S.12315ORCID

Affiliation:

1. Department of Electrical and Computer Engineering, National University of Singapore, Singapore 117583, Singapore.

2. Institute for Health Innovation and Technology, National University of Singapore, Singapore 117599, Singapore.

3. The N.1 Institute for Health, National University of Singapore, Singapore 117456, Singapore.

4. Department of Biomedical Engineering, National University of Singapore, Singapore 117583, Singapore.

5. Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore.

6. Skin Research Institute of Singapore, Singapore 308232, Singapore.

7. Nanyang Institute of Technology in Health and Medicine, Interdisciplinary Graduate Programme, Nanyang Technological University, Singapore 637335, Singapore.

8. Institute of Molecular and Cell Biology, A*STAR, Singapore 138669, Singapore.

9. Faculty of Dentistry, National University of Singapore, Singapore 119085, Singapore.

10. Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore 117585, Singapore.

11. Attonics Systems Pte Ltd., Singapore 079903, Singapore.

12. Singapore Synchrotron Light Source, National University of Singapore, Singapore 117603, Singapore.

13. Department of Materials Science and Engineering, National University of Singapore, Singapore 117575, Singapore.

14. St Luke’s Hospital, Singapore 659674, Singapore.

15. Graduate School of Integrative Sciences and Engineering, National University of Singapore, Singapore 117456, Singapore.

16. Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.

17. Department of Chemistry, National University of Singapore, Singapore 117544, Singapore.

Abstract

A wireless sensor based on bioresponsive DNA hydrogel provides smartphone-based detection of wound infection.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Multidisciplinary

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