Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo-Reference-Cited by-同舟云学术

Alveolar macrophages generate a noncanonical NRF2-driven transcriptional response to Mycobacterium tuberculosis in vivo

Published:2019-07-05 Issue:37 Volume:4 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Rothchild Alissa C.¹^ORCID,Olson Gregory S.¹²^ORCID,Nemeth Johannes¹^ORCID,Amon Lynn M.¹^ORCID,Mai Dat¹^ORCID,Gold Elizabeth S.¹,Diercks Alan H.¹,Aderem Alan¹^ORCID

Affiliation:

1. Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, WA 98109, USA.

2. Medical Scientist Training Program, University of Washington School of Medicine, Seattle, WA 98195, USA.

Abstract

Induction of an NRF2-dependent cell-protective signature impairs alveolar macrophages from controlling M.tb. infection in vivo.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference71 articles.

1. Building a tuberculosis-free world: The Lancet Commission on tuberculosis;Reid M. J. A.;Lancet,2019

2. Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

3. Understanding and overcoming the barriers to T cell-mediated immunity against tuberculosis;Urdahl K. B.;Semin. Immunol.,2014

4. Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs

5. Mycobacterium tuberculosis Infects Dendritic Cells with High Frequency and Impairs Their Function In Vivo

Cited by 117 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. USP8 promotes intracellular infection by enhancing ESCRT-mediated membrane repair, limiting xenophagy, and reducing oxidative stress;Autophagy;2024-09-11

2. TGFβ primes alveolar-like macrophages to induce type I IFN following TLR2 activation;2024-09-08

3. Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice;Nature Microbiology;2024-09-06

4. Mycobacterium tuberculosis infection induces a novel type of cell death: Ferroptosis;Biomedicine & Pharmacotherapy;2024-08

5. Revisiting the role of hypoxia-inducible factors and nuclear factor erythroid 2-related factor 2 in regulating macrophage inflammation and metabolism;Frontiers in Cellular and Infection Microbiology;2024-07-25