Tuft cell–produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation-Reference-Cited by-同舟云学术

Tuft cell–produced cysteinyl leukotrienes and IL-25 synergistically initiate lung type 2 inflammation

Published:2021-12-24 Issue:66 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Ualiyeva Saltanat¹^ORCID,Lemire Evan²^ORCID,Aviles Evelyn C.³^ORCID,Wong Caitlin¹^ORCID,Boyd Amelia A.¹^ORCID,Lai Juying¹,Liu Tao¹,Matsumoto Ichiro⁴,Barrett Nora A.¹^ORCID,Boyce Joshua A.¹^ORCID,Haber Adam L.²^ORCID,Bankova Lora G.¹^ORCID

Affiliation:

1. Division of Allergy and Clinical Immunology, Jeff and Penny Vinik Center for Allergic Disease Research, Brigham and Women’s Hospital and Department of Medicine, Harvard Medical School, Boston, MA, USA.

2. Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA.

3. Department of Neurobiology, Harvard Medical School, Boston, MA, USA.

4. Monell Chemical Senses Center, Philadelphia, PA, USA.

Abstract

Tuft cells produce LTC 4 and IL-25, which cooperate to promote allergen-driven airway inflammation.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference78 articles.

1. Allergens and the airway epithelium response: Gateway to allergic sensitization

2. Barrier Epithelial Cells and the Control of Type 2 Immunity