Preferential induction of cross-group influenza A hemagglutinin stem–specific memory B cells after H7N9 immunization in humans-Reference-Cited by-同舟云学术

Preferential induction of cross-group influenza A hemagglutinin stem–specific memory B cells after H7N9 immunization in humans

Published:2017-07-21 Issue:13 Volume:2 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Andrews Sarah F.¹^ORCID,Joyce M. Gordon¹^ORCID,Chambers Michael J.¹^ORCID,Gillespie Rebecca A.¹^ORCID,Kanekiyo Masaru¹^ORCID,Leung Kwanyee¹,Yang Eun Sung¹,Tsybovsky Yaroslav²,Wheatley Adam K.³^ORCID,Crank Michelle C.¹,Boyington Jeffrey C.¹^ORCID,Prabhakaran Madhu S.¹,Narpala Sandeep R.¹,Chen Xuejun¹^ORCID,Bailer Robert T.¹,Chen Grace¹^ORCID,Coates Emily¹^ORCID,Kwong Peter D.¹^ORCID,Koup Richard A.¹,Mascola John R.¹,Graham Barney S.¹^ORCID,Ledgerwood Julie E.¹,McDermott Adrian B.¹^ORCID

Affiliation:

1. Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

2. Electron Microscopy Laboratory, Cancer Research Technology Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21701, USA.

3. Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.

Abstract

Broadly protective antibodies are preferentially induced upon vaccination with a group 2 immunogen.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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