Type 3 cytokines IL-17A and IL-22 drive TGF-β–dependent liver fibrosis-Reference-Cited by-同舟云学术

Type 3 cytokines IL-17A and IL-22 drive TGF-β–dependent liver fibrosis

Published:2018-10-26 Issue:28 Volume:3 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Fabre Thomas¹²^ORCID,Molina Manuel Flores¹²^ORCID,Soucy Geneviève¹³,Goulet Jean-Philippe⁴,Willems Bernard¹⁵,Villeneuve Jean-Pierre¹⁵,Bilodeau Marc¹⁵^ORCID,Shoukry Naglaa H.¹⁵^ORCID

Affiliation:

1. Centre de Recherche du Centre hospitalier de l’Université de Montréal (CRCHUM), Montréal, Québec, Canada.

2. Département de microbiologie, infectiologie et immunologie, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada.

3. Département de pathologie et biologie cellulaire, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada.

4. Caprion, Montréal, Québec, Canada.

5. Département de médecine, Faculté de médecine, Université de Montréal, Montréal, Québec, Canada.

Abstract

Type 3 immune response defined by increased IL-22 production drives fibrosis during chronic liver injury via enhanced TGF-β signaling.

Funder

Canadian Institutes of Health Research

Fonds de Recherche du Québec - Santé

Canadian Liver Foundation

Fonds de recherche du Québec – Santé (FRQS) AIDS and Infectious Disease Network

Canadian Network on Hepatitis C

Novartis/Canadian Liver Foundation Hepatology Research Chair

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference51 articles.

1. Pathogenesis of Liver Fibrosis

2. The 3 major types of innate and adaptive cell-mediated effector immunity

3. Interferon gamma decreases hepatic stellate cell activation and extracellular matrix deposition in rat liver fibrosis

4. Type 2 immunity in tissue repair and fibrosis

5. Regulation of TH17 Cells and Associated Cytokines in Wound Healing, Tissue Regeneration, and Carcinogenesis

Cited by 98 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Unraveling IL-17 and IL-22 role in occult hepatitis C versus chronic hepatitis C virus infection;BMC Infectious Diseases;2024-01-25

2. Distinct fibroblast functions associated with fibrotic and immune-mediated inflammatory diseases and their implications for therapeutic development;F1000Research;2024-01-10

3. Cellular Interactions and Crosstalk Facilitating Biliary Fibrosis in Cholestasis;Cellular and Molecular Gastroenterology and Hepatology;2024-01

4. Age‐associated Senescent – T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response;Advanced Materials;2023-12-28

5. Antifibrotic Effect of Selenium-Containing Nanoparticles on a Model of TAA-Induced Liver Fibrosis;Cells;2023-11-28