OAS1/RNase L executes RIG-I ligand–dependent tumor cell apoptosis-Reference-Cited by-同舟云学术

OAS1/RNase L executes RIG-I ligand–dependent tumor cell apoptosis

Published:2021-07-29 Issue:61 Volume:6 Page:
ISSN:2470-9468
Container-title:Science Immunology
language:en
Short-container-title:Sci. Immunol.

Author:

Boehmer Daniel F. R.¹²^ORCID,Formisano Simone²^ORCID,de Oliveira Mann Carina C.³^ORCID,Mueller Stephan A.⁴⁵^ORCID,Kluge Michael⁶^ORCID,Metzger Philipp²^ORCID,Rohlfs Meino⁷,Hörth Christine²,Kocheise Lorenz²^ORCID,Lichtenthaler Stefan F.⁴⁵⁸^ORCID,Hopfner Karl-Peter³⁹^ORCID,Endres Stefan²⁹¹⁰^ORCID,Rothenfusser Simon²¹⁰^ORCID,Friedel Caroline C.⁶^ORCID,Duewell Peter¹¹^ORCID,Schnurr Max²,Koenig Lars M.²^ORCID

Affiliation:

1. Department of Medicine II, University Hospital, LMU Munich, 81377 Munich, Germany.

2. Division of Clinical Pharmacology, University Hospital, LMU Munich, 80337 Munich, Germany.

3. Gene Center Munich and Department of Biochemistry, Ludwig-Maximilians-Universität, Munich, Germany.

4. German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.

5. Neuroproteomics, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.

6. Institute of Informatics, Ludwig-Maximilians-Universität München, 80333 Munich, Germany.

7. Dr. von Hauner Children’s Hospital, Department of Pediatrics, University Hospital, LMU Munich, 80337 Munich, Germany.

8. Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

9. Center of Integrated Protein Science Munich (CIPS-M), LMU Munich, Munich, Germany.

10. Einheit für Klinische Pharmakologie (EKLIP), Helmholtz Zentrum Muenchen, Neuherberg, Germany.

11. Institute of Innate Immunity, University Hospital Bonn, University of Bonn, 53127 Bonn, Germany.

Abstract

5′-Triphosphate RNA–induced apoptosis consists of a RIG-I–dependent priming and an OAS1/RNase L–dependent effector phase.

Funder

H2020 Marie Skłodowska-Curie Actions

Deutsche Forschungsgemeinschaft

Else Kröner-Fresenius-Stiftung

Elitenetzwerk Bayern

Friedrich-Baur-Stiftung

Munich Cluster for Systems Neurology

IMMUTRAIN

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

Reference74 articles.

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5. 5'-Triphosphate RNA Is the Ligand for RIG-I

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