Cross-reactive antibodies against human coronaviruses and the animal coronavirome suggest diagnostics for future zoonotic spillovers

Author:

Klompus Shelley12ORCID,Leviatan Sigal12,Vogl Thomas12ORCID,Mazor Roei D.3ORCID,Kalka Iris N.12ORCID,Stoler-Barak Liat3ORCID,Nathan Nachum3,Peres Ayelet4ORCID,Moss Lihee3,Godneva Anastasia12ORCID,Tikva Sharon Kagan Ben3ORCID,Shinar Eilat5,Cohen-Dvashi Hadas6,Gabizon Ronen6,London Nir6ORCID,Diskin Ron6ORCID,Yaari Gur4ORCID,Weinberger Adina12ORCID,Shulman Ziv3ORCID,Segal Eran12ORCID

Affiliation:

1. Department of Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot 76100, Israel.

2. Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel.

3. Department of Immunology, Weizmann Institute of Science, Rehovot 76100, Israel.

4. Faculty of Engineering, Bar Ilan University, Ramat Gan 52900, Israel.

5. Magen David Adom Blood Services, Ramat Gan 52900, Israel.

6. Department of Chemical and Structural Biology, Weizmann Institute of Science, Rehovot 7610001, Israel.

Abstract

Cross-reactive antibodies present after SARS-CoV-2 infection can distinguish patients with COVID-19 from uninfected individuals.

Funder

Seerave Foundation

Austrian Science Fund

Israel Science Foundation

Miel de Botton and the Corona Response Fund at the Weizmann Institute of Science

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine,Immunology

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