iRhom2 inhibits bile duct obstruction–induced liver fibrosis-Reference-Cited by-同舟云学术

iRhom2 inhibits bile duct obstruction–induced liver fibrosis

Published:2019-10-29 Issue:605 Volume:12 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Sundaram Balamurugan¹^ORCID,Behnke Kristina¹^ORCID,Belancic Andrea¹,Al-Salihi Mazin A.¹^ORCID,Thabet Yasser²,Polz Robin³^ORCID,Pellegrino Rossella⁴,Zhuang Yuan¹,Shinde Prashant V.¹,Xu Haifeng C.¹,Vasilevska Jelena¹,Longerich Thomas⁴,Herebian Diran⁵,Mayatepek Ertan⁵^ORCID,Bock Hans H.²,May Petra²,Kordes Claus²⁶^ORCID,Aghaeepour Nima⁷,Mak Tak W.⁸⁹,Keitel Verena²,Häussinger Dieter²⁶,Scheller Jürgen³,Pandyra Aleksandra A.¹²,Lang Karl S.¹⁰,Lang Philipp A.¹^ORCID

Affiliation:

1. Department of Molecular Medicine II, Medical Faculty, Heinrich-Heine-University Düsseldorf, Universitätsstrasse 1, 40225 Düsseldorf, Germany.

2. Department of Gastroenterology, Hepatology, and Infectious Diseases, Heinrich-Heine-University Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany.

3. Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.

4. Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany.

5. Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.

6. Institute for Experimental Regenerative Hepatology, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.

7. Stanford University, 300 Pasteur Drive, Grant S280, Stanford, CA 94305-5117, USA.

8. Department of Medical Biophysics, University of Toronto, 1 King’s Circle, Toronto, ON M5S 1A8, Canada.

9. Department of Pathology, University of Hong Kong, Hong Kong.

10. Institute of Immunology, Medical Faculty, University of Duisburg-Essen, Hufelandstr. 55, Essen 45147, Germany.

Abstract

iRhom2 reduces hepatic stellate cell activation and liver fibrosis after bile duct ligation.

Funder

German Research Council

Molecules of Infection

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference70 articles.

1. Liver inflammation and fibrosis

2. The global burden of liver disease: a challenge for methods and for public health

3. Contemporary epidemiology of chronic liver disease and cirrhosis;Moon A. M.;Clin. Gastroenterol. Hepatol.,2019

4. Origin of myofibroblasts in the fibrotic liver in mice

5. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Temporal analysis of lung injury induced by real‐ambient PM₂_.5 exposure in mice;Environmental Toxicology;2023-10-02

2. MicroRNA-30a depresses hepatic stellate cell activation against liver fibrosis through blockade of the TGF-β1/Smad2/3 pathway;Biotechnology and Genetic Engineering Reviews;2023-04-05

3. The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth;Life Science Alliance;2023-01-31

4. Immunomodulatory role of metalloproteinase ADAM17 in tumor development;Frontiers in Immunology;2022-11-17

5. The ADAM17 sheddase complex regulator iTAP modulates inflammation, epithelial repair, and tumor growth;2022-04-12