G protein signaling–biased agonism at the κ-opioid receptor is maintained in striatal neurons-Reference-Cited by-同舟云学术

G protein signaling–biased agonism at the κ-opioid receptor is maintained in striatal neurons

Published:2018-08-07 Issue:542 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ho Jo-Hao¹^ORCID,Stahl Edward L.¹,Schmid Cullen L.¹,Scarry Sarah M.²^ORCID,Aubé Jeffrey²^ORCID,Bohn Laura M.¹^ORCID

Affiliation:

1. Departments of Molecular Medicine and Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.

2. UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Abstract

Triazole 1.1 is a G protein–biased agonist of the κ-opioid receptor in striatal neurons.

Funder

NIH Office of the Director

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

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