A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca 2+ permeation and SOCE-induced gene transcription-Reference-Cited by-同舟云学术

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca 2+ permeation and SOCE-induced gene transcription

Published:2015-12-22 Issue:408 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Frischauf Irene¹,Zayats Vasilina²³,Deix Michael¹,Hochreiter Anna¹⁴,Jardin Isaac¹,Muik Martin¹,Lackner Barbara¹,Svobodová Barbora¹⁵,Pammer Teresa¹,Litviňuková Monika¹,Sridhar Amrutha Arumbakam¹,Derler Isabella¹,Bogeski Ivan⁶,Romanin Christoph¹,Ettrich Rüdiger H.²³,Schindl Rainer¹

Affiliation:

1. Institute of Biophysics, JKU Life Science Center, Johannes Kepler University Linz, Gruberstrasse 40, 4020 Linz, Austria.

2. Center for Nanobiology and Structural Biology, Institute of Microbiology, Academy of Sciences of the Czech Republic, Zamek 136, CZ-373 33 Nove Hrady, Czech Republic.

3. Faculty of Sciences, University of South Bohemia, Zamek 136, CZ-373 33 Nove Hrady, Czech Republic.

4. Institute of Experimental and Clinical Cell Therapy, Paracelsus Medical University, A-5020 Salzburg, Austria.

5. Institute of Biophysics, Medical University of Graz, A-8010 Graz, Austria.

6. Department of Biophysics, School of Medicine, University of Saarland, D-66421 Homburg, Germany.

Abstract

A special region of the store-operated calcium channel maintains channel function under conditions of low extracellular calcium.

Funder

Austrian Science Fund (FWF)

BMWF HRSM

Czech Science Foundation

German Research Foundation (DFG)

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference54 articles.

1. ORAI1 and STIM1 deficiency in human and mice: roles of store-operated Ca2+entry in the immune system and beyond

2. CRAC channels and Ca2+signaling in mast cells

3. Ion channels and transporters in lymphocyte function and immunity

4. Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

5. Emerging roles of store-operated Ca2+entry through STIM and ORAI proteins in immunity, hemostasis and cancer

Cited by 53 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Similarities and Differences between the Orai1 Variants: Orai1α and Orai1β;International Journal of Molecular Sciences;2022-11-23

2. PKC-Mediated Orai1 Channel Phosphorylation Modulates Ca2+ Signaling in HeLa Cells;Cells;2022-06-27

3. Science CommuniCa2+tion Developing Scientific Literacy on Calcium: The Involvement of CRAC Currents in Human Health and Disease;Cells;2022-06-05

4. STIM and Orai Mediated Regulation of Calcium Signaling in Age-Related Diseases;Frontiers in Aging;2022-04-19

5. The Role of Lipids in CRAC Channel Function;Biomolecules;2022-02-23