Affiliation:
1. Novartis Institutes for BioMedical Research, Novartis Pharma AG, Basel, Switzerland.
Abstract
Organ size and function critically depend on the tight regulation of cellular turnover. In this issue of
Science Signaling,
Trinh
et al
. reveal that hepatic stellate cells play an important role in maintaining liver homeostasis by stimulating midzonal hepatocyte proliferation through the secretion of neurotrophin-3.
Publisher
American Association for the Advancement of Science (AAAS)
Subject
Cell Biology,Molecular Biology,Biochemistry