The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication-Reference-Cited by-同舟云学术

The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication

Published:2015-12-08 Issue:406 Volume:8 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ingle Harshad¹,Kumar Sushil¹,Raut Ashwin Ashok²,Mishra Anamika²,Kulkarni Diwakar Dattatraya²,Kameyama Takeshi³,Takaoka Akinori³,Akira Shizuo⁴,Kumar Himanshu¹⁴

Affiliation:

1. Laboratory of Immunology, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal 462066, India.

2. Pathogenomics Lab, OIE Reference Lab for Avian Influenza, ICAR-National Institute of High Security Animal Diseases, Bhopal 462022, India.

3. Division of Signaling in Cancer and Immunology, Institute for Genetic Medicine, Hokkaido University, Sapporo 060-0815, Japan.

4. Laboratory of Host Defense, WPI Immunology Frontier Research Centre, Osaka University, Osaka 565-0871, Japan.

Abstract

A single miRNA exhibits both an inhibitory effect on the antiviral response and an antiviral effect on viral replication.

Funder

IISER Bhopal institutional fellowship

CSIR India Senior research fellowship

Department of Science and Technology (DST), India

DST and Department of Biotechnology, Government of India

IISER Bhopal-IGM Hokkaido University

Intramural Research Grant of IISER, Bhopal, India

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference54 articles.

1. Pattern Recognition Receptors and Inflammation

2. Nucleic Acid Recognition by the Innate Immune System

3. RIG-I-like receptors: cytoplasmic sensors for non-self RNA

4. Cytosolic Sensing of Viruses

5. Innate Immune Sensing and Signaling of Cytosolic Nucleic Acids

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