The Rfx4 Transcription Factor Modulates Shh Signaling by Regional Control of Ciliogenesis-Reference-Cited by-同舟云学术

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The Rfx4 Transcription Factor Modulates Shh Signaling by Regional Control of Ciliogenesis

Published:2009-11-03 Issue:95 Volume:2 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Ashique Amir M.¹,Choe Youngshik²,Karlen Mattias³,May Scott R.⁴,Phamluong Khanhky¹,Solloway Mark J.¹,Ericson Johan³,Peterson Andrew S.¹

Affiliation:

1. Department of Molecular Biology, Genentech, South San Francisco, CA 94080, USA.

2. Department of Neurology, University of California at San Francisco, San Francisco, CA 94158, USA.

3. Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm SE-171 77, Sweden.

4. Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, CA 92186, USA.

Abstract

Rfx4 regulates the formation of primary cilia, thereby playing a crucial role in central nervous system development.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference45 articles.

1. The Hedgehog Signaling Pathway in Cancer

2. The Gli code: an information nexus regulating cell fate, stemness and cancer

3. Mechanisms of ventral patterning in the vertebrate nervous system

4. Vertebrate Smoothened functions at the primary cilium

5. Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function

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