5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein–coupled receptor D-Reference-Cited by-同舟云学术

5-oxoETE triggers nociception in constipation-predominant irritable bowel syndrome through MAS-related G protein–coupled receptor D

Published:2018-12-18 Issue:561 Volume:11 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Bautzova Tereza¹,Hockley James R. F.²³^ORCID,Perez-Berezo Teresa¹,Pujo Julien¹^ORCID,Tranter Michael M.³^ORCID,Desormeaux Cleo¹,Barbaro Maria Raffaella⁴^ORCID,Basso Lilian¹,Le Faouder Pauline⁵,Rolland Corinne¹,Malapert Pascale⁶,Moqrich Aziz⁶,Eutamene Helene⁷,Denadai-Souza Alexandre¹^ORCID,Vergnolle Nathalie¹⁸^ORCID,Smith Ewan St John²^ORCID,Hughes David I.⁹,Barbara Giovanni⁴,Dietrich Gilles¹,Bulmer David C.²³^ORCID,Cenac Nicolas¹^ORCID

Affiliation:

1. INSERM, UMR1220, IRSD, Université de Toulouse, INRA, ENVT, UPS, Toulouse, France.

2. Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB1 2PD, UK.

3. National Centre for Bowel Research and Surgical Innovation, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 2AJ, UK.

4. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

5. INSERM UMR1048, Lipidomic Core Facility, Metatoul Platform, Université de Toulouse, Toulouse, France.

6. Aix-Marseille-Université, CNRS, Institut de Biologie du Développement de Marseille, UMR 7288, Marseille, France.

7. Neuro-Gastroenterology and Nutrition Team, UMR 1331, INRA Toxalim, INP-EI-Purpan, Université de Toulouse, Toulouse, France.

8. Departments of Physiology & Pharmacology, and Medicine, University of Calgary Cumming School of Medicine, 3330 Hospital Drive Northwest, Calgary, Alberta T2N 4N1, Canada.

9. Institute of Neuroscience and Psychology, University of Glasgow, Glasgow, UK.

Abstract

Sensory neurons expressing the GPCR Mrgprd mediate the effects of a bioactive lipid to cause abdominal pain.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference64 articles.

1. Bowel Disorders

2. Irritable bowel syndrome

3. Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions

4. Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome

5. Mast Cell-Dependent Excitation of Visceral-Nociceptive Sensory Neurons in Irritable Bowel Syndrome

Cited by 45 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transcriptomic profiling reveals a pronociceptive role for angiotensin II in inflammatory bowel disease;Pain;2024-01-29

2. Alamandine injection in the periaqueductal gray and rostral ventromedial medulla attenuates allodynia induced by sciatic nerve ligation in rats;Neuroscience Letters;2024-01

3. Proenkephalin deletion in hematopoietic cells induces intestinal barrier failure resulting in clinical feature similarities with irritable bowel syndrome in mice;Communications Biology;2023-11-16

4. Medium-chain and long-chain fatty acids are associated with diarrheal predominant irritable bowel syndrome revealed by DESI-MSI;Journal of Gastroenterology;2023-08-14

5. ALPK1 Expressed in IB4-Positive Neurons of Mice Trigeminal Ganglions Promotes MIA-Induced TMJ pain;Molecular Neurobiology;2023-07-13