Genome-wide identification and characterization of Notch transcription complex–binding sequence-paired sites in leukemia cells-Reference-Cited by-同舟云学术

Genome-wide identification and characterization of Notch transcription complex–binding sequence-paired sites in leukemia cells

Published:2017-05-02 Issue:477 Volume:10 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Severson Eric¹^ORCID,Arnett Kelly L.²^ORCID,Wang Hongfang¹^ORCID,Zang Chongzhi³^ORCID,Taing Len³,Liu Hudan⁴,Pear Warren S.⁴^ORCID,Shirley Liu X.³^ORCID,Blacklow Stephen C.²^ORCID,Aster Jon C.¹^ORCID

Affiliation:

1. Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA.

2. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

3. Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard School of Public Health, Boston, MA 02114, USA.

4. Department of Pathology and Laboratory Medicine, Abramson Family Cancer Research Institute, Institute of Medicine and Engineering, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

Abstract

Paired regulation of protein-coding genes and enhancer noncoding RNAs tunes Notch signaling in leukemia.

Funder

National Institutes of Health

Leukemia and Lymphoma Society

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference47 articles.

1. The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism

2. p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1