Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability-Reference-Cited by-同舟云学术

Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability

Published:2016-05-17 Issue:428 Volume:9 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Zvezdova Ekaterina¹,Mikolajczak Judith²³⁴⁵,Garreau Anne²³⁴⁵,Marcellin Marlène⁶,Rigal Lise²³⁴⁵,Lee Jan¹,Choi Seeyoung¹,Blaize Gaëtan²³⁴⁵,Argenty Jérémy²³⁴⁵,Familiades Julien²³⁴⁵,Li Liqi¹,Gonzalez de Peredo Anne⁶,Burlet-Schiltz Odile⁶,Love Paul E.¹,Lesourne Renaud²³⁴⁵

Affiliation:

1. Section on Cellular and Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

2. Centre de Physiopathologie de Toulouse Purpan, Toulouse F-31300, France.

3. Institut National de la Santé et de la Recherche Médicale, U1043, Toulouse F-31300, France.

4. Centre National de la Recherche Scientifique, U5282, Toulouse F-31300, France.

5. Université de Toulouse, Université Paul Sabatier, Toulouse F-31300, France.

6. Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, Toulouse F-31077, France.

Abstract

The protein Themis1 enables thymocyte selection by promoting T cell receptor signaling.

Funder

INSERM

Sanofi

Intramural Research Program of the Eunice Kennedy Shriver, National Institute of Child Health and Human Development

Fondation pour la Recherche sur la Sclerose en Plaque (ARSEP)