Prostaglandin E 2 –EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms-Reference-Cited by-同舟云学术

Prostaglandin E 2 –EP2–NF-κB signaling in macrophages as a potential therapeutic target for intracranial aneurysms

Published:2017-02-07 Issue:465 Volume:10 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Aoki Tomohiro¹²,Frȍsen Juhana³⁴⁵,Fukuda Miyuki¹,Bando Kana⁶⁷,Shioi Go⁷,Tsuji Keiichi⁸,Ollikainen Eliisa³,Nozaki Kazuhiko⁸,Laakkonen Johanna⁹,Narumiya Shuh¹²

Affiliation:

1. Center for Innovation in Immunoregulation Technology and Therapeutics, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.

2. Core Research for Evolutional Science and Technology, Medical Innovation Center, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.

3. Neurosurgery Research Group, Biomedicum Helsinki, Helsinki 00029 HUS, Finland.

4. Hemorrhagic Brain Pathology Research Group, NeuroCenter, Kuopio University Hospital, Kuopio 70029 KYS, Finland.

5. Department of Neurosurgery, NeuroCenter, Kuopio University Hospital, Kuopio 70029 KYS, Finland.

6. Animal Resource Development Unit, RIKEN Center for Life Science Technologies, Hyogo 650-0047, Japan.

7. Genetic Engineering Team, RIKEN Center for Life Science Technologies, Hyogo 650-0047, Japan.

8. Department of Neurosurgery, Shiga University of Medical Science, Shiga 520-2192, Japan.

9. Department of Molecular Medicine, A.I. Virtanen Institute, University of Eastern Finland, Kuopio 70211, Finland.

Abstract

Inhibition of prostaglandin E 2 signaling in macrophages may be a pharmacological option for treating intracranial aneurysms.

Funder

Core Research for Evolutional Science and Technology Program on Chronic Inflammation

Japan Science and Technology Agency

Finnish Medical Foundation

Kuopio University Hospital

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference59 articles.

1. Subarachnoid haemorrhage

2. Editorial

3. Prevalence and Risk of Rupture of Intracranial Aneurysms

4. Safety and occlusion rates of surgical treatment of unruptured intracranial aneurysms: a systematic review and meta-analysis of the literature from 1990 to 2011

5. Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies

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