The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells-Reference-Cited by-同舟云学术

The kinase IRAK4 promotes endosomal TLR and immune complex signaling in B cells and plasmacytoid dendritic cells

Published:2020-06-02 Issue:634 Volume:13 Page:
ISSN:1945-0877
Container-title:Science Signaling
language:en
Short-container-title:Sci. Signal.

Author:

Corzo Cesar A.¹^ORCID,Varfolomeev Eugene¹^ORCID,Setiadi A. Francesca¹,Francis Ross¹^ORCID,Klabunde Sha¹,Senger Kate¹^ORCID,Sujatha-Bhaskar Swathi¹,Drobnick Joy¹,Do Steven¹,Suto Eric¹^ORCID,Huang Zhiyu¹,Eastham-Anderson Jeffrey¹,Katewa Arna¹,Pang Jodie¹^ORCID,Domeyer Melanie¹,Dela Cruz Christopher¹^ORCID,Paler-Martinez Andres¹^ORCID,Lau Vivian W. C.¹^ORCID,Hadadianpour Azadeh¹,Ramirez-Carrozi Vladimir¹^ORCID,Sun Yonglian¹^ORCID,Bao Katherine¹^ORCID,Xu Daqi¹,Hunley Emily¹,Brightbill Hans D.¹^ORCID,Warming Soren¹^ORCID,Roose-Girma Merone¹^ORCID,Wong Alfred¹^ORCID,Tam Lucinda¹^ORCID,Emson Claire L.¹,Crawford James J.¹^ORCID,Young Wendy B.¹,Pappu Rajita¹,McKenzie Brent S.¹^ORCID,Asghari Vida¹,Vucic Domagoj¹^ORCID,Hackney Jason A.¹^ORCID,Austin Cary D.¹^ORCID,Lee Wyne P.¹^ORCID,Lekkerkerker Annemarie¹^ORCID,Ghilardi Nico¹^ORCID,Bryan Marian C.¹^ORCID,Kiefer James R.¹^ORCID,Townsend Michael J.¹,Zarrin Ali A.¹^ORCID

Affiliation:

1. Research, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.

Abstract

Inhibiting the kinase IRAK4 may suppress a multicellular autoinflammatory loop in patients with lupus.

Publisher

American Association for the Advancement of Science (AAAS)

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference73 articles.

1. Systemic lupus erythematosus

2. Belimumab in systemic lupus erythematosus

3. Association of plasma B lymphocyte stimulator levels and disease activity in systemic lupus erythematosus

4. New therapies for systemic lupus erythematosus — past imperfect, future tense

5. New insights into the immunopathogenesis of systemic lupus erythematosus

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Animal models of systemic lupus erythematosus (SLE);Dubois' Lupus Erythematosus and Related Syndromes;2025

2. The innate immune system in SLE;Dubois' Lupus Erythematosus and Related Syndromes;2025

3. Interleukin‐1 receptor‐associated kinase 4 (IRAK4) is a critical regulator of inflammatory signalling through toll‐like receptors 4 and 7/8 in murine and human lungs;British Journal of Pharmacology;2024-08-13

4. Ro60—Roles in RNA Processing, Inflammation, and Rheumatic Autoimmune Diseases;International Journal of Molecular Sciences;2024-07-14

5. Human and Murine Toll-like Receptor-Driven Disease in Systemic Lupus Erythematosus;International Journal of Molecular Sciences;2024-05-14